P.+Reproductive+Physiology

 **I. Sexual Reproduction ** *Fertilization occurs when fusion between a sperm cell and an egg cell (ovum) *These cells are known as germ cells or gametes *We have typically 46 chromosomes in a human cell *During the cell division in reproduction it is halved so each gamete receives 23 chromosomes *The gametes go through a process of reduction division, we mainly know it as Meiosis *Eventually, the zygote will grow through mitotic cell divisions and mature through puberty
 * REPRODUCTIVE PHYSIOLOGY **

**II. Male Reproductive System ** *In the male system, pituitary secretion of LH is controlled by negative feedback from testosterone and the secretion of FSH is controlled by the secretion of inhibin from the testes *Testosterone promotes growth of soft tissue in bones before the epuphyseal discs have sealed in our body *Testosterone and similar related androgens are actually anabolic steroids *Leydig cells stimulated by LH secrete testosterone *The Leydig cells and the Sertoli cells are responsible and important for secreting autocrine regulatory molecules that allow the inerstitual and tublar compartments to work together

**III. Female Reproductive System ** *During prophase, there are oocytes that are contained in the primordial folliciles in the ovary and their number is maximal at birth and declines after that *In each cycle only a small number of oocytes are stimulated and become secondary *After the first meiotic division, the other product that eventually disintegrates in a tiny polar body *The hypothalmus us responsible for secreting GnRH *5 months of gestation occur after the germ cells migrate into the ovaries during early embryonic development  A **APPLICATION:** Working in a pharmacy in an inpatient hospital pharmacy setting we have a delivery floor for women to deliver their children. We produce and keep them stocked with several medication for pain management and also familiar and commonly used drugs for delivery. One that stands out in my mind is oxytocin. We deliver it in an IV bag that is delievered to help maintain the muscle tone and to reduce any hemorrhaging. It can also reduce the size of the uterus after delivery. Also, my best friend is a NICU nurse (also is an on-call NICU flight nurse! YAH FOR LINDSEY!) and she has been able to share a lot with me and allowed me to even shadow this past year at her work. Once you get into dosing beyond the parent for babies it is a whole other realm in pharmacy. It is very interesting though and one drug that stands out is when children are born and there lungs seem to be not developed completely we draw a two series injection and acts as a steroid. It is truly amazing!  **Sources:**  **http://www.nicerweb.com/bio1152/Locked/media/ch13/13_05HumanLifeCycle.jpg**
 * http://www.topnews.in/usa/files/pregnant-lady.jpg**